Work

Biocatalytic Asymmetric Synthesis of Chiral Amines from Ketones Applied to Sitagliptin Manufacture

Year: 2010

Type: article

Source: Science

DOI: 10.1126/science.1188934

Authors: Christopher K. Savile, Jacob M. Janey, Emily C. Mundorff, Jeffrey C. Moore, Sarena Tam, William R. Jarvis, Jeffrey C. Colbeck, Anke Krebber, Fred J. Fleitz, Jos Brands, Paul N. Devine, Gjalt W. Huisman, Gregory J. Hughes

Institutions: Codexis (United States), Merck & Co., Inc., Rahway, NJ, USA (United States)

Language: English

Topic: Enzyme Catalysis and Immobilization

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: closed

OpenAlex ID: W1986056153

FWCI: 27.9

Cites: 24

Cited by: 1,791

Related to: 10