Work

Anticancer activity of cardiac glycosides

Year: 2012

Type: article

Abstract: Retrospective clinical data indicate that cardiac glycosides (CGs), notably digoxin, prolong the survival of carcinoma patients treated with conventional chemotherapy. CGs are known to influence the immune response at multiple levels. In addition, recent results suggest that CGs trigger the immunogenic demise of cancer cells, an effect that most likely contributes to their clinical anticancer activity.

Source: OncoImmunology

DOI: 10.4161/onci.21684

Authors: Oliver Kepp, Laurie Menger, Erika Vacchelli, Sandy Adjemian, Isabelle Martins, Yuting Ma, Abdul Qader Sukkurwala, Mickaël Michaud, Lorenzo Galluzzi, Laurence Zitvogel, Guido Kroemer

Institutions: Université Paris-Sud, Inserm, Institut Gustave Roussy, Sorbonne Paris Cité, Centre de Recherche des Cordeliers, Université Paris Descartes, Délégation Paris 5, Assistance Publique – Hôpitaux de Paris, Hôpital Européen Georges-Pompidou

Language: English

Topic: Phytochemistry and Bioactive Compounds

Subfield: Biomaterials

Field: Materials Science

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,913

OpenAlex ID: W1986085836

FWCI: 2.852

Cites: 14

Cited by: 105

Related to: 10