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Catalytic, enantioselective 1,3-dipolar cycloadditions of nitrile imines with methyleneindolinones

Year: 2013

Type: article

Abstract: Catalytic, enantioselective 1,3-dipolar cycloadditions of nitrile imines with methyleneindolinones are reported. The spiro[pyrazolin-3,3'-oxindole] products are formed in good yields (up to 98%) and high enantioselectivity (up to 99% ee).

Source: Organic & Biomolecular Chemistry

DOI: 10.1039/c3ob41815d

Authors: Anthony L. Gerten, Michael C. Slade, Kelsie M. Pugh, Levi M. Stanley

Institution: Iowa State University

Language: English

Topic: Asymmetric Synthesis and Catalysis

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: green

Funders: Howard Hughes Medical Institute, National Institute of General Medical Sciences

Awards: Directed Evolution of Metal-Substituted Carbonic Anhydrases for Catalysis, G8289487879, Directed Evolution of Metal-Substituted Carbonic Anhydrases: Applications as Cat

OpenAlex ID: W1986095231

FWCI: 2.425

Cites: 29

Cited by: 47

Related to: 10