Work

FA iPS: correction or reprogramming first?

Year: 2012

Type: article

Abstract: In this issue of Blood, Mu ¨ller et al show that Fanconi anemia (FA) cells are resistant, but not completely refractory, to reprogramming into induced pluripotent stem (iPS) cells. 1 Genetic complementation before reprogramming restores DNA repair, rescues reprogramming, and yields iPS cells less likely to contain genetic alterations.

Source: Blood

DOI: 10.1182/blood-2012-04-417246

Author: Eirini P. Papapetrou

Institution: University of Washington

Language: English

Topic: Pluripotent Stem Cells Research

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: bronze

Funder: National Institute of Diabetes and Digestive and Kidney Diseases