Work

Understanding the Complexity of the Immune System during Pregnancy

Year: 2014

Type: review

Abstract: Progress in our understanding of the role of the maternal immune system during healthy pregnancy will help us better understand the role of the immune system in adverse pregnancy outcomes. In this review, we discuss our present understanding of the 'immunity of pregnancy' in the context of the response to cervical and placental infections and how these responses affect both the mother and the fetus. We discuss novel and challenging concepts that help explain the immunological aspects of pregnancy and how the mother and fetus respond to infection.

Source: American Journal of Reproductive Immunology

DOI: 10.1111/aji.12289

Authors: Karen Racicot, Ja‐Young Kwon, Paulomi Aldo, Michelle Silasi, Gil Mor

Institution: Yale University

Language: English

Topic: Reproductive System and Pregnancy

Subfield: Immunology

Field: Immunology and Microbiology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

Funder: Eunice Kennedy Shriver National Institute of Child Health and Human Development