Year: 2003
Type: review
Abstract: A γ-aminobutyric acid (GABA)-ergic theory of mood disorders was proposed by Emrich and colleagues (1980) following observations of the efficacy of the GABAergic anticonvulsant, valproate, in the treatment of mania. Since then, increasing biochemical and pharmacological evidence from animal and human studies has supported the hypothesis that mood disorders are associated with abnormalities in brain GABA function.
Source: Psychological Medicine
Authors: M. TAYLOR, Z. BHAGWAGAR, P. J. COWEN, T. SHARP
Institutions: Warneford Hospital, University of Oxford
Language: English
Subfield: Cellular and Molecular Neuroscience
Field: Neuroscience
Domain: Life Sciences
Open Access status: bronze
Funder: University of Cambridge
OpenAlex ID: W1986763467