Work

Dysregulation of 5‐HT Function in Bulimia Nervosa

Year: 1989

Type: article

Abstract: Bulimia nervosa, which is related to anorexia nervosa and affective illness, is likely to involve serotonin (5-HT) dysregulation.'In double-blind, randomized fashion, agematched women with bulimia nervosa and healthy female controls were challenged with rn-chlorophenylpiperazine (rn-CPP, 0.5 mg/kg P.o.), a postsynaptic 5-HT agonist, and L-tryptophan (L-TRP, 100 mg/kg i.v.), the dietary precursor of 5-HT.Subjects and methods have been described in detail elsewhere.1.2

Source: Annals of the New York Academy of Sciences

DOI: 10.1111/j.1749-6632.1989.tb53274.x

Authors: TIMOTHY BREWERTON, EDWARD MULLER, HARRY BRANDT, MICHAEL LESEM, ARLENE HEGG, DENNIS MURPHY, DAVID JIMERSON

Institutions: Medical University of South Carolina, National Institute of Mental Health

Language: English

Topic: Eating Disorders and Behaviors

Subfield: Clinical Psychology

Field: Psychology

Domain: Social Sciences

SDG: Good health and well-being

Open Access status: bronze

OpenAlex ID: W1986969582

FWCI: 1.539

Cites: 6

Cited by: 10

Related to: 10