Work

Tissue engineering: strategies, stem cells and scaffolds

Year: 2008

Type: review

Abstract: Tissue engineering scaffolds are designed to influence the physical, chemical and biological environment surrounding a cell population. In this review we focus on our own work and introduce a range of strategies and materials used for tissue engineering, including the sources of cells suitable for tissue engineering: embryonic stem cells, bone marrow-derived mesenchymal stem cells and cord-derived mesenchymal stem cells. Furthermore, we emphasize the developments in custom scaffold design and manufacture, highlighting laser sintering, supercritical carbon dioxide processing, growth factor incorporation and zoning, plasma modification of scaffold surfaces, and novel multi-use temperature-sensitive injectable materials.

Source: Journal of Anatomy

DOI: 10.1111/j.1469-7580.2008.00878.x

Authors: Daniel Howard, Lee D. Buttery, Kevin M. Shakesheff, Scott J. Roberts

Institution: University of Nottingham

Language: English

Topic: Bone Tissue Engineering Materials

Subfield: Biomedical Engineering

Field: Engineering

Domain: Physical Sciences

Open Access status: green

Funder: Biotechnology and Biological Sciences Research Council

Award: G516177370