Work

Late Onset CNS Immune Reconstitution Inflammatory Syndrome in an Immunocompetent Patient

Year: 2013

Type: article

Abstract: Immune reconstitution inflammatory syndrome (IRIS) refers to the presence of paradoxical clinical deterioration attributable to immune system recovery during highly active antiretroviral therapy (HAART). We present an immunocompetent patient with multifocal leukoencephalopathy on HAART, with central nervous system (CNS) IRIS pathology of unknown infectious etiology. CNS IRIS pathology should be suspected in patients on longstanding HAART without immune reconstitution, presenting with unexplained leukoencephalopathy.

Source: Frontiers in Neurology

DOI: 10.3389/fneur.2013.00012

Authors: Alejandro Hornik, Federico Rodriguez-Porcel, Shawn Wallery, Murray Flaster, John M. Lee, José Biller

Institutions: Loyola University Medical Center, Loyola University Chicago, Loyola Medicine

Language: English

Topic: Infectious Diseases and Tuberculosis

Subfield: Surgery

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $3,801