Work

Stem celltherapy for ischemic heart failure.

Year: 2005

Type: article

Abstract: As the prevalence and incidence of ischemic heart disease continue to increase, so does interest in ischemic heart failure management. Limitations of current therapies have led to research aimed at regenerating and repairing ischemically damaged myocardium through stem-cell therapy. Cell types being evaluated include embryonic stem cells, fetal and neonatal cardiomyocytes, skeletal myoblasts, bone marrow stem cells, peripheral blood CD34+ cells, endothelial progenitor cells, cardiac progenitor cells, and fibroblasts. Preclinical animal studies and promising early results of clinical trials now under way suggest that stem-cell therapy may soon become an important new tool in heart failure management.

Source: Europe PMC (PubMed Central)

Authors: Doreen Rosenstrauch, Gregor Poglajen, Nina Zidar, Igor D Gregoric

Institution: Baylor St. Luke's Medical Center

Language: English

Topic: Mesenchymal stem cell research

Subfield: Cell Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W1987925810

FWCI: 1.291

Cites: 48

Cited by: 57

Related to: 10