Work

Confocal imaging studies cast doubt on nuclear localization of JAK2V617F

Year: 2011

Type: article

Abstract: To the editor: The most common mutation in myeloproliferative neoplasm (MPN) substitutes a valine to phenylalanine at position 617 of JAK2 ( JAK2 V617F).[1][1]Recently, Rinaldi et al reported both a nuclear and cytoplasmic localization of JAK2 in K562 cells.[2][2] A previous report also indicated

Source: Blood

DOI: 10.1182/blood-2011-02-336479

Authors: François Girodon, Mara P. Steinkamp, Cédric Cleyrat, Sylvie Hermouet, Bridget S. Wilson

Institutions: University of New Mexico, Inserm, Centre Hospitalier Universitaire de Nantes, UNM Comprehensive Cancer Center

Language: English

Topic: Myeloproliferative Neoplasms: Diagnosis and Treatment

Subfield: Genetics

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funder: National Institute of General Medical Sciences