Extracellular Matrix Heterogeneity Regulates Three‐Dimensional Morphologies of Breast Adenocarcinoma Cell Invasion
Year: 2012
Type: article
Abstract: Plasticity and reciprocity of breast cancer cells to various extracellular matrice (ECMs) are three-dimensionally analyzed in quantitative way in a novel and powerful microfluidic in vitro platform. This successfully demonstrates the metastatic potential of cancer cells and their effective strategies of ECM proteolytic remodeling and morphological change, while interacting with other cells and invading into heterogeneous ECMs.
Source: Advanced Healthcare Materials
Language: English
Subfield: Cell Biology
Domain: Life Sciences
Open Access status: green
Funder: National Cancer Institute
Award: G5064473834
OpenAlex ID: W1988516042