Work

SOLVE and RESOLVE: automated structure solution, density modification and model building

Year: 2003

Type: article

Abstract: The software SOLVE and RESOLVE can carry out all the steps in macromolecular structure solution, from scaling and heavy-atom location through phasing, density modification and model-building in the MAD, SAD and MIR cases. SOLVE uses scoring scheme to convert the decision-making in macromolecular structure solution to an optimization problem. RESOLVE carries out the identification of NCS, density modification and automated model-building. The procedure is fully automated and can function at resolutions as low as 3 A.

Source: Journal of Synchrotron Radiation

DOI: 10.1107/s0909049503023938

Author: Thomas Terwilliger

Institution: Los Alamos National Laboratory

Language: English

Topic: Enzyme Structure and Function

Subfield: Structural Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: hybrid

Estimated APC paid: $3,180

OpenAlex ID: W1988647322