Work

Plant and Animal Sensors of Conserved Microbial Signatures

Year: 2010

Type: article

Abstract: The last common ancestor of plants and animals may have lived 1 billion years ago. Plants and animals have occasionally exchanged genes but, for the most part, have countered selective pressures independently. Microbes (bacteria, eukaryotes, and viruses) were omnipresent threats, influencing the direction of multicellular evolution. Receptors that detect molecular signatures of infectious organisms mediate awareness of nonself and are integral to host defense in plants and animals alike. The discoveries leading to elucidation of these receptors and their ligands followed a similar logical and methodological pathway in both plant and animal research.

Source: Science

DOI: 10.1126/science.1189468

Authors: Pamela C. Ronald, Bruce Beutler

Institutions: Kyung Hee University, Joint BioEnergy Institute, University of California, Davis, Scripps Research Institute

Language: English

Topic: Immune Response and Inflammation

Subfield: Immunology

Field: Immunology and Microbiology

Domain: Life Sciences

Open Access status: green

OpenAlex ID: W1988652189

FWCI: 11.24

Cites: 28

Cited by: 254

Related to: 10