Year: 2009
Type: article
Abstract: Adducted DNA, it's not so hard to find. I tried to reach for you, but you're so hard to bind. Whatever happened to your groove? I wish I understood. It used to be so nice, but lesions are no good! When RecA's near me, filaments will cleave me, SOS! LexA is cleave-ing, repression is leave-ing, SOS! Get thee gone! Thymine dimer just doesn't belong! UvrB Binds at lesions, so they can be cleaved. Pol III just cannot bypass all these lesions here. Polymerases switch, good thing Pol IV is near! The beta clamp is at the rear. DNA should not fear. Pols IV and V, they come to the rescue, my dear! When RecA's near me, filaments will cleave me, SOS! If I am LexA, MucA, or UmuD, SOS! Get thee gone! 6–4 adduct just doesn't belong. UmuC Is as mutagenic as can be. Double strands breaking, and all this mutating, SOS! RecA you gave me, nothing else could save me, SOS! Get thee gone! Benzo-[a]-pyrene just doesn't belong Here comes Lon Pol V's work's done, and now it is gone. Mutant genes? NER does just what the cell needs Let's be fair— We're better with DNA repair! Additional Supporting Information may be found in the online version of this article. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
DOI: 10.1002/bmb.20305
Authors: Sharotka M. Simon, Lauren S. Waters, Daniel F. Jarosz, Penny J. Beuning
Language: English
Subfield: Education
Field: Social Sciences
Domain: Social Sciences
Open Access status: bronze
OpenAlex ID: W1989021646