Year: 1991
Type: article
Abstract: Banan® (cefpodoxime proxetil CPDX-PR) was administered to 177 patients with infections in the department of otorhinolaryngology, and its clinical and bacteriological effects, and its concentration in tissue and blood were determined.The clinical effect was 90.5% for acute otitis media, 59.0% for chronic otitis media, 92.0% for acute sinusitis, 84.2% for chronic sinusitis, and 88.2% for tonsillitis. The bacteriological bacterial elimination rate was 82.4% for acute otitis media, 62.5% for chronic otitis media, 88.9% for acute sinusitis, 64.7% for chronic sinusitis, and 91.3% for tonsillitis.The concentration of the drug in tissue was 0.25 to 0.70μ/ml, and the concentration in blood was 0.12 to 2.45μg/ml.Side effects were not observed in any of the cases.
Source: Practica Oto-Rhino-Laryngologica
Authors: Kiyoshi Yonei, Hiroki Kimura, Kiyotaka Murata, Fumihiko Ota, Yasuhiro Yoshioka, Yoshikiyo Sakaguchi, Keizo Morimatsu, Kenichi Shimada, Motoaki Kato, Kaori Tanaka, Hiroshi Ito, Yoshiaki Tsuta, Masahiko Harata, Takayo Yanagawa, Katsuhiko Tamaki, Yoshihisa Nakai
Language: English
Subfield: Pharmacology
Field: Medicine
Domain: Health Sciences
Open Access status: bronze
OpenAlex ID: W1989744416