Work

Dynamic membrane patterning, signal localization and polarity in living cells

Year: 2014

Type: review

Abstract: We review the molecular and physical aspects of the dynamic localization of signaling molecules on the plasma membranes of living cells. At the nanoscale, clusters of receptors and signaling proteins play an essential role in the processing of extracellular signals. At the microscale, "soft" and highly dynamic signaling domains control the interaction of individual cells with their environment. At the multicellular scale, individual polarity patterns control the forces that shape multicellular aggregates and tissues.

Source: Soft Matter

DOI: 10.1039/c4sm02157f

Authors: M. Zamparo, F. Chianale, C. Tebaldi, M. Cosentino-Lagomarsino, M. Nicodemi, A. Gamba

Institutions: Istituto Nazionale di Fisica Nucleare, Politecnico di Torino, National Interuniversity Consortium for the Physical Sciences of Matter, Italian institute for Genomic Medicine, Centre National de la Recherche Scientifique, Université Pierre-et-Marie-Curie

Language: English

Topic: Lipid Membrane Structure and Behavior

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: bronze

OpenAlex ID: W1989966056

FWCI: 0.063

Cites: 165

Cited by: 11

Related to: 10