Work

Ligands in crystal structures that aid in functional characterization

Year: 2010

Type: article

Abstract: Liganded structures can be instrumental in assigning function to uncharacterized proteins by revealing active sites, conserved residues, binding motifs, and substrate specificity. This introduction provides an overview and commentary on the value of liganded structures emerging from the JCSG structural genomics initiative.

Source: Acta Crystallographica Section F Structural Biology and Crystallization Communications

DOI: 10.1107/s1744309110035748

Authors: Anna E. Speers, Benjamin F. Cravatt

Institution: Scripps Research Institute

Language: English

Topic: Enzyme Structure and Function

Subfield: Materials Chemistry

Field: Materials Science

Domain: Physical Sciences

Open Access status: hybrid

OpenAlex ID: W1990622898

FWCI: 0.309

Cites: 9

Cited by: 6

Related to: 10