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Direct evidence that ribosome bound RNA-dependent RNA polymerase does not play a role in globin messenger RNA replication

Year: 1977

Type: article

Abstract: The radioactively labelled product of RNA-dependent RNA polymerase+ from ribosomes of immature chicken erythrocytes was tested for the presence of newly replicated globin mRNA using unlabelled globin complementary DNA. No radioactively labelled globin mRNA sequences were found in the product, providing direct confirmation that this RNA-dependent RNA polymerase is not involved in globin mRNA amplification.

Source: Nucleic Acids Research

DOI: 10.1093/nar/4.2.461

Authors: Charles D. Boyd, W. Fitschen

Institution: University of Cape Town

Language: English

Topic: RNA and protein synthesis mechanisms

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: green

Funders: Coordenação de Aperfeiçoamento de Pessoal de Nível Superior, University of Cape Town

OpenAlex ID: W1990706838

FWCI: 0.74

Cites: 10

Cited by: 5

Related to: 10