Intrinsically disordered proteins and their (disordered) proteomes in neurodegenerative disorders
Year: 2015
Type: article
Abstract: The recent years have witnessed a rise in the number of intrinsically disor-dered proteins (IDPs), also known as hybrid proteins, which possess both struc-tured domains and biologically important intrinsically disordered protein regions (IDPRs). These proteins challenge the “one sequence—one structure—one func-tion ” concept by demonstrating that the lack of stable tertiary and/or secondary structure does not preclude proteins from being biologically active (Wright
Source: Frontiers in Aging Neuroscience
Author: Vladimir N. Uversky
Language: English
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: gold
Estimated APC paid: $3,801
Funder: Russian Science Foundation
Award: G4351622268
OpenAlex ID: W1991017805