Year: 1999
Type: review
Abstract: Many cellular processes, including embryogenesis (1-4), gene expression (5), cell cycle (6), programmed cell death (7), intracellular protein targeting (8) and endocrine/neural functions (9-13) are regulated by limited proteolysis of precursor proteins (14,15). These functions are carried out by proteolytic enzyme families that are strategically localized within cells or on cell surfaces (3,5-7, 9, 10). This review focuses on the serine proteases that process protein precursors (proproteins) traversing the secretory pathway (for recent reviews, see Refs.
Source: Journal of Biological Chemistry
Authors: An Zhou, Gene Webb, Xiaorong Zhu, Donald F. Steiner
Institutions: Howard Hughes Medical Institute, University of Chicago
Language: English
Subfield: Cancer Research
Domain: Life Sciences
Open Access status: hybrid
Estimated APC paid: $3,430
Awards: G2807054497, G3394385110
OpenAlex ID: W1991263759