Work

Thermoelastic displacement measured by DP-OCT for detecting vulnerable plaques

Year: 2014

Type: article

Abstract: The detection of thermoelastic displacement by differential phase optical coherence tomography (DP-OCT) was analytically evaluated for identifying atherosclerotic plaques. Analytical solutions were developed to understand the dynamics of physical distribution of point hear sources during/after laser irradiation on thermoelastic responses of MION-injected tissue. Both analytical and experimental results demonstrated a delayed peak displacement along with slow decay after laser pulse due to heterogeneous distribution of the point heat sources. Detailed description of the heat sources in tissue as well as integration of a scanning mirror can improve computational accuracy as well as clinical applicability of DP-OCT for diagnosing vulnerable plaque.

Source: Biomedical Optics Express

DOI: 10.1364/boe.5.000474

Authors: Jihoon Kim, Hyun Wook Kang, Junghwan Oh, Thomas E. Milner

Institutions: Samsung (South Korea), Samsung Electronics (South Korea), Pukyong National University, The University of Texas at Austin

Language: English

Topic: Optical Coherence Tomography Applications

Subfield: Biomedical Engineering

Field: Engineering

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,913