Work

Structure and Function of HIV-1 Reverse Transcriptase: Molecular Mechanisms of Polymerization and Inhibition

Year: 2008

Type: review

Source: Journal of Molecular Biology

DOI: 10.1016/j.jmb.2008.10.071

Authors: Stefan G. Sarafianos, Bruno Marchand, Kalyan Das, Daniel M. Himmel, Michael A. Parniak, Stephen H. Hughes, Eddy Arnold

Institutions: University of Missouri, Rutgers, The State University of New Jersey, University of Pittsburgh, National Cancer Institute

Language: English

Topic: HIV/AIDS drug development and treatment

Subfield: Infectious Diseases

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funders: National Institutes of Health, National Institute of General Medical Sciences, National Institute of Allergy and Infectious Diseases

Awards: G1213099975, G1705206532, G1767093982, Bisphosphonate inhibitors of NRTI excision, Microbicide properties of RT inhibitor combinations, G2837090080, HIV-1 reverse transcriptase structure: function, inhibition, and resistance, Microbicide properties of RT inhibitor combinations, G582976923, G613375395, Ultrapotent Inhibitors of Wild-type and Multi-drug Resistant HIV, HIV RNase H natural product inhibitors, G8156908395, Evolving understanding of HIV-1 reverse transcriptase structure, function, and inhibition., Gene Therapy for HIV Using Aptamers that Target Reverse Transcriptase, Ultrapotent Inhibitors of Wild-type and Multi-drug Resistant HIV, Structure-Based Design of Drugs and Vaccines for Target*

OpenAlex ID: W1991492628

FWCI: 3.519

Cites: 166

Cited by: 543

Related to: 10