Work

Complementary Electrical and Spectroscopic Detection Assays with On‐Wire‐Lithography‐Based Nanostructures

Year: 2009

Type: article

Abstract: On-wire lithography is used to synthesize a new nanostructure composed of a goldpolypyrrole segment and gold nanodisk pairs for parallel electrical and spectroscopic readout (see image). As proof-of-concept, the binding of telomerase to surface-functionalized oligonucleotide receptors and subsequent elongation of the oligonucleotides are demonstrated by parallel electrical and spectroscopic measurements.

Source: Small

DOI: 10.1002/smll.200901000

Authors: Gengfeng Zheng, Xiaodong Chen, Chad A. Mirkin

Institutions: Northwestern University, International Institute for Nanotechnology

Language: English

Topic: Advanced biosensing and bioanalysis techniques

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: green

Funder: National Institutes of Health

Award: G9000165630