Work

Clinical and Microbiological Aspects of Chemotherapeutic Agents Used According to the Specific Plaque Hypothesis

Year: 1979

Type: article

Abstract: Certain forms of dental decay and periodontal disease appear to be due to specific bacterial infections following overgrowth of certain indigenous plaque bacteria, i.e., the specific plaque hypothesis, If so, then antimicrobial treatment based on a diagnosis of elevated levels or proportions of these organisms should be considered. Such treatment cannot be administered according to concepts of the non-specific plaque hypothesis. A treatment philosophy is presented which is based upon considerations long established in medical infections following overgrowth of certain indigenous plaque bacteria, i.e., the specific plaque hypomicrobial to the site of the infection for periods long enough to suppress or destroy the pathogenic agent. Examples of this treatment philosophy are given.

Source: Journal of Dental Research

DOI: 10.1177/00220345790580120905

Author: Walter J. Loesche

Institution: University of Michigan

Language: English

Topic: Oral microbiology and periodontitis research

Subfield: Periodontics

Field: Dentistry

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funder: National Institutes of Health