Work

Supramolecular gel phase crystallization: orthogonal self-assembly under non-equilibrium conditions

Year: 2013

Type: review

Abstract: This tutorial review charts the history of gel phase crystallization from its origins in Liesegang ring formation to current research in the generation of new pharmaceutical solid forms in low molecular weight organogels. The growth of molecular crystals under a supersaturation gradient within the same space and timescale as the formation of a gel phase material is placed into context as an example of orthogonal self-assembly. Such multi-component, weakly coupled orthogonal self-assembly processes occurring far from equilibrium represent a powerful conceptual paradigm for generating fascinating emergent behaviour in chemical systems.

Source: Chemical Society Reviews

DOI: 10.1039/c3cs60224a

Authors: D. Krishna Kumar, Jonathan W. Steed

Institution: Durham University

Language: English

Topic: Supramolecular Self-Assembly in Materials

Subfield: Biomaterials

Field: Materials Science

Domain: Physical Sciences

Open Access status: green

Funder: Engineering and Physical Sciences Research Council

Award: Complementary Gel and Microemulsion Strategies for Pharmaceutical Solid Form Control