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Unveiling an exceptional zymogen: the single-chain form of tPA is a selective activator of NMDA receptor-dependent signaling and neurotoxicity

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Year: 2012
Type: article
Source: Cell Death and Differentiation
DOI: 10.1038/cdd.2012.86
Authors: J Parcq, T Bertrand, A Montagne, A F Baron, R Macrez, J M Billard, A Briens, Y Hommet, J Wu, M Yepes, H R Lijnen, P Dutar, E Anglés-Cano, D Vivien
Institutions: Inserm, Serine Proteases and Pathophysiology of the neurovascular Unit, Centre for Psychiatry and Neuroscience, Université Paris Descartes, Emory University, KU Leuven
Language: English

Topic: Neuroscience and Neuropharmacology Research
Subfield: Cellular and Molecular Neuroscience
Field: Neuroscience
Domain: Life Sciences
SDG: Good health and well-being

Open Access status: bronze

Funders: U.S. Department of Veterans Affairs, Institut National de la Santé et de la Recherche Médicale, National Institutes of Health, National Heart, Lung, and Blood Institute, National Institute of Neurological Disorders and Stroke
Awards: G2018614394, Protease-Regulated Blood Brain Barrier Permeability, G3182099668, G4051179110, G5544374816, G679502749, G9000296872
OpenAlex ID: W1992444994
FWCI: 1.199
Cites: 40
Cited by: 73
Related to: 10
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