Local Positive Feedback Regulation Determines Cell Shape in Root Hair Cells
Year: 2008
Type: article
Abstract: The specification and maintenance of growth sites are tightly regulated during cell morphogenesis in all organisms. ROOT HAIR DEFECTIVE 2 reduced nicotinamide adenine dinucleotide phosphate (RHD2 NADPH) oxidase-derived reactive oxygen species (ROS) stimulate a Ca2+ influx into the cytoplasm that is required for root hair growth in Arabidopsis thaliana. We found that Ca2+, in turn, activated the RHD2 NADPH oxidase to produce ROS at the growing point in the root hair. Together, these components could establish a means of positive feedback regulation that maintains an active growth site in expanding root hair cells. Because the location and stability of growth sites predict the ultimate form of a plant cell, our findings demonstrate how a positive feedback mechanism involving RHD2, ROS, and Ca2+ can determine cell shape.
Source: Science
Authors: Seiji Takeda, Catherine Gapper, Hidetaka Kaya, Elizabeth Bell, Kazuyuki Kuchitsu, Liam Dolan
Institutions: John Innes Centre, Tokyo University of Science
Language: English
Subfield: Plant Science
Domain: Life Sciences
Open Access status: green
Funders: Ministry of Education, Culture, Sports, Science and Technology, Directorate for Biological Sciences, U.S. Geological Survey, Biotechnology and Biological Sciences Research Council, Natural Environment Research Council, Japan Society for the Promotion of Science, Lawrence Berkeley National Laboratory
OpenAlex ID: W1992702812