Roles of mast cells and basophils in innate and acquired immunity
Year: 2000
Type: review
Abstract: There have been several recent advances in knowledge about mast cells and basophils in immune responses, of which some are particularly important: a role has been found for heparin in the storage of certain proteases and other mediators in mast cell cytoplasmic granules; an important role for mast cells in the development of several chronic aspects of an asthma model in mice has been discovered; and a new approach has been developed, based on the generation of mast cells from embryonic stem cells in vitro, to investigate mast cell function in vitro or in vivo.
Source: Current Opinion in Immunology
Authors: Jochen Wedemeyer, Mindy Tsai, Stephen J Galli
Institutions: Stanford Medicine, Stanford University
Language: English
Topic: Mast cells and histamine
Subfield: Immunology
Field: Immunology and Microbiology
Domain: Life Sciences
Open Access status: hybrid
Estimated APC paid: $4,410
OpenAlex ID: W1993091864
