Work

Surgical sealants and high strength adhesives

Year: 2015

Type: article

Abstract: Traditional methods for closing a surgical wound include the use of sutures, wires, and staples. However, despite their extensive use, these techniques have several limitations. For example, they are time-consuming, may cause further tissue trauma, increase the risk of infection and are difficult to use in some surgical locations. Moreover, none of these techniques create immediate and proper sealing. A promising alternative to the traditional closure techniques are surgical sealants. High strength surgical adhesives grow at over 15% compound annual growth rate (CAGR 2012–2017) in the U.S. [1]. Surgical sealants and adhesives can be used as adjuncts to sutures to prevent air and liquid leakages. They can also potentially replace sutures and staples for better closure, minimized blood loss, faster implementation, and easy and less painful operation without the need for removal. Various biomaterials have been developed to attach tissues and seal the wounds, or to glue devices to tissues. The main challenge toward designing a surgical sealant/adhesive is to achieve sufficient adhesion strength to the tissues in the wet environment without impairing the biocompatibility and tissue function. In

Source: Materials Today

DOI: 10.1016/j.mattod.2015.02.012

Authors: Mehdi Kazemzadeh-Narbat, Nasim Annabi, Ali Khademhosseini

Institutions: Brigham and Women's Hospital, Harvard University

Language: English

Topic: Surgical Sutures and Adhesives

Subfield: Surgery

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $6,070