Work

An improved human carboxylesterase for enzyme/prodrug therapy with CPT-11

Year: 2008

Type: article

Source: Cancer Gene Therapy

DOI: 10.1038/sj.cgt.7701112

Authors: M Wierdl, L Tsurkan, J L Hyatt, C C Edwards, M J Hatfield, C L Morton, P J Houghton, M K Danks, M R Redinbo, P M Potter

Institutions: St. Jude Children's Research Hospital, University of North Carolina at Chapel Hill

Language: English

Topic: Virus-based gene therapy research

Subfield: Genetics

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: closed

Funders: National Institute on Drug Abuse, National Cancer Institute

Awards: G1139922818, G1192453550, G2569337406, SELECTIVE THERAPY OF TUMORS THAT OVEREXPRESS C MYC, G2911273532, G4616587371, Improving CPT-11 Efficacy Using Structural and Chemical Biology, Studies of Childhood Solid Tumors, G5330097265, Selective inhibitors to improve CPT-11 therapy, Novel Therapeutic Approaches for Narcotic Overdose, Selective Therapy of Neuroblastoma

OpenAlex ID: W1993546715

FWCI: 2.461

Cites: 37

Cited by: 49

Related to: 10