Work

Real-time quantitative visualization of 3D structural information

Year: 2012

Type: article

Abstract: We demonstrate a novel approach for the real time visualization and quantification of the 3D spatial frequencies in an image domain. Our approach is based on the spectral encoding of spatial frequency principle and permits the formation of an image as a color map in which spatially separated spectral wavelengths correspond to the dominant 3D spatial frequencies of the object. We demonstrate that our approach can visualize and analyze the dominant axial internal structure for each image point in real time and with nanoscale sensitivity to structural changes. Computer modeling and experimental results of instantaneous color visualization and quantification of 3D structures of a model system and biological samples are presented.

Source: Optics Express

DOI: 10.1364/oe.20.009203

Authors: Sergey A. Alexandrov, Shikhar Uttam, Rajan K. Bista, Chengquan Zhao, Yang Liu

Institutions: University of Pittsburgh, Magee-Womens Hospital, University of Pittsburgh Medical Center

Language: English

Topic: Advanced Optical Imaging Technologies

Subfield: Media Technology

Field: Engineering

Domain: Physical Sciences

Open Access status: gold

Estimated APC paid: $2,270

Funder: National Cancer Institute