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Chiral Spaces: Dissymmetric Capsules Through Self-Assembly

Year: 1998

Type: article

Abstract: Molecules with self-complementary surfaces interact through weak intermolecular forces to form assemblies, and the assembled states frequently exhibit distinctive properties. Described here are systems in which symmetrical molecules assemble through hydrogen bonding to produce capsules with dissymmetric cavities. The capsules form and dissipate on a time scale that permits their direct observation by nuclear magnetic resonance measurements, and they act as hosts for smaller molecular guests. Molecular recognition of chiral guests, such as naturally occurring terpenes, determines which dissymmetric cavities are preferentially formed in the assembly process.

Source: Science

DOI: 10.1126/science.279.5353.1021

Authors: José M. Rivera, Tomás Martı́n, Julius Rebek

Institutions: Scripps Research Institute, Massachusetts Institute of Technology

Language: English

Topic: Supramolecular Chemistry and Complexes

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: green

OpenAlex ID: W1994014392

FWCI: 12.69

Cites: 20

Cited by: 199

Related to: 10