Work

MR myocardial perfusion analysis of first-pass enhancement kinetics with a lagrangian approach

Year: 2014

Type: article

Abstract: Background Observation of the kinetics of tissue enhancement after the injection of a bolus of tracer has been used for the analysis of perfusion and related variables. In general, a gradient of concentration in the exchanging vascular compartment between the ar terial and venous ends is represented in models via focus on maintaining the detailed balance between the advective and diffusive exchange processes. Conventionally, this is by considering the exchange in an Eulerian framework, based on considering the exchange within each compartment as a separate unit (e.g., tissue homogeneity (TH) model [1]). Herein, we present a Lagrangian approach to the exchange modeling, such that the blood flowing between compartments is considered as the primary unit, and, thereby, allowing for coarser discretization and more efficient calculations (Figure 1a). Methods

Source: Journal of Cardiovascular Magnetic Resonance

DOI: 10.1186/1532-429x-16-s1-p203

Authors: Sohae Chung, Binita Shah, Sohah Iqbal, James Slater, Leon Axel

Institutions: NYU Langone Health, New York University

Language: English

Topic: Cardiac Imaging and Diagnostics

Subfield: Radiology, Nuclear Medicine and Imaging

Field: Medicine

Domain: Health Sciences

Open Access status: gold

Estimated APC paid: $3,000

Funder: National Institutes of Health