Work

Effect of trazodone in a single dose before bedtime for sleep disorders accompanied by a depressive state: Dose‐finding study with no concomitant use of hypnotic agent

Year: 1999

Type: article

Abstract: This was the first dose-finding study of trazodone that was designed to be free of the concomitant use of hypnotics, in which the drug was administered in a single dose for sleep disorders combined with a depressive state. As a result, trazodone at the dosage of 50-100 mg/day improved sleep disorders, particularly at the 100 mg/day dosage. It was confirmed that trazodone improved sleep disorders combined with a depressive state when it was administered in a single dose before bedtime with no concomitant hypnotics.

Source: Psychiatry and Clinical Neurosciences

DOI: 10.1046/j.1440-1819.1999.00532.x

Authors: Hirobumi Mashiko, Shin‐Ichi Niwa, Hisashi Kumashiro, Yoshihiro Kaneko, Satoru Suzuki, Yoshihiko Numata, Ryu Horikoshi, Yoshinori Watanabe

Institutions: Fukushima Medical University, Shirakawa Kosei General Hospital, Fukushima Red Cross Hospital, Fukuchiyama City Hospital

Language: English

Topic: Sleep and related disorders

Subfield: Experimental and Cognitive Psychology

Field: Psychology

Domain: Social Sciences

SDG: Good health and well-being

Open Access status: bronze

OpenAlex ID: W1995128400

FWCI: 1.177

Cites: 2

Cited by: 35

Related to: 10