Molecular characterization of a ranavirus isolated from largemouth bass Micropterus salmoides
Year: 1999
Type: article
Abstract: An iridovirus, isolated from largemouth bass Micropterus salmoides following a die-off among adult fish and provisionally designated largemouth bass virus (LMBV), was characterized by analysis of viral protein synthesis in infected cells, viral DNA restriction fragment length polymorphisms (RFLP), and sequence determination of the major capsid protein and viral DNA methyltransferase genes. All 3 approaches yielded results consistent with the suggestion that LMBV was a member of the genus Ranavirus. Moreover, LMBV was nearly identical to 2 isolates from Southeast Asia which had been previously detected in imported ornamental fish. It remains to be determined whether infection of largemouth bass resulted from exposure to an imported virus, or whether the presence of similar viruses in southeast Asia and the southeastern United States indicates that iridovirus species are not geographically limited as suggested earlier, but rather globally distributed.
Source: Diseases of Aquatic Organisms
DOI: 10.3354/dao037107
Authors: J Mao, J Wang, GD Chinchar, VG Chinchar
Institutions: University of Mississippi Medical Center, Tougaloo College
Language: English
Subfield: Immunology
Field: Immunology and Microbiology
Domain: Life Sciences
Open Access status: bronze
Funder: U.S. Department of Agriculture
OpenAlex ID: W1995136006