Work

Effects of aging on parathyroid hormones stimulated ionic fluxes in rat parotid cell aggregates

Year: 1987

Type: article

Abstract: The effects of aging on parathyroid hormone stimulated calcium and phosphate efflux from isolated rat parotid cell aggregates differed from that of epinephrine stimulated calcium efflux in magnitude, chronology, and ionic dependence. Parathyroid stimulated ionic fluxes were maximal at 1-3 months of age, declined until 12 months and remained constant thereafter. Epinephrine stimulated calcium efflux remained maximal between 3 and 12 months and declined until at least 24 months. Absolute stimulation of calcium efflux over basal levels was maximal at 4-8% while phosphate efflux was 20-30%.

Source: Mechanisms of Ageing and Development

DOI: 10.1016/0047-6374(87)90020-0

Authors: Masataka Shiraki, Yasuko Ishikawa, Bruce J. Baum, George S. Roth

Institutions: National Institutes of Health, Johns Hopkins Bayview Medical Center, National Institute on Aging, National Institute of Dental and Craniofacial Research

Language: English

Topic: Salivary Gland Disorders and Functions

Subfield: Physiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $4,780