Work

Strategies for the Preparation of Differentially Protectedortho-Prenylated Phenols

Year: 2002

Type: article

Abstract: A new process for ortho-prenylation of phenols is presented within the context of known methods. All of the processes are briefly assessed with regards to the substitution patterns and accompanying functional groups tolerated by each strategy. The conclusion reached is that a new procedure using ortho-quinone methides, for which an experimental protocol is provided, offers the greatest generality and flexibility in the preparation of ortho-prenylated phenol derivatives.

Source: Synlett

DOI: 10.1055/s-2003-36234

Authors: Thomas R. Pettus, Christophe Hoarau

Institution: University of California, Santa Barbara

Language: English

Topic: Chemical Synthesis and Reactions

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: green

Funders: National Science Foundation, National Institute of General Medical Sciences

Award: The Synthesis and Application of Novel Aromatic Materials