Work

P 1 ,P 2 -Diimidazolyl derivatives of pyrophosphate and bis-phosphonates – synthesis, properties, and use in preparation of dinucleoside tetraphosphates and analogs

Year: 2010

Type: article

Abstract: P(1),P(2)-Diimidazolyl derivatives of pyrophosphate and halomethylene-bis-phosphonates have been synthesized and characterized, and the mechanism of their formation was studied. These reagents enable synthesis of dinucleoside tetraphosphates and tetraphosphonates conveniently and in high yields.

Source: Organic & Biomolecular Chemistry

DOI: 10.1039/c0ob00542h

Authors: Ivan B. Yanachkov, Edward J. Dix, Milka I. Yanachkova, George E. Wright

Institution: Glsynthesis

Language: English

Topic: Organophosphorus compounds synthesis

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: green

Funder: National Heart, Lung, and Blood Institute

Awards: Diadenosine Boranotetraphosph(on)ates as Antithrombotic Drugs, G4956205573, Novel Antithrombotic Diadenosine Tetraphosphate Analogs, G6000646730, Novel Antithrombotic Diadenosine Tetraphosphate Analogs