Year: 1956
Type: article
Abstract: A preliminary electron microscope study has revealed the presence in lysosome-rich fractions, isolated from rat liver, of hitherto undescribed cytoplasmic particles, called "dense bodies." Approximately 0.37 micro in length, the dense bodies often possess an internal cavity and external membrane. They contain many electron-dense granules 55 to 77 A, or less, in diameter. Such dense bodies are also visible in electron micrographs of parenchymatous cells in liver sections. The correlations between dense bodies and lysosomes are listed, but until pure preparations are available it is not possible to assert that dense bodies and lysosomes are identical.
Source: The Journal of Cell Biology
DOI: 10.1083/jcb.2.4.179
Authors: Alex B. Novikoff, H. Beaufay, C. de Duve
Institutions: Albert Einstein College of Medicine, Yeshiva University
Language: English
Subfield: Cell Biology
Domain: Life Sciences
Open Access status: green
OpenAlex ID: W1995616301