Year: 2010
Type: article
Abstract: In January 1910, a century ago, Thomas Hunt Morgan discovered his first Drosophila mutant, a white-eyed male (Morgan 1910). Morgan named the mutant gene white and soon demonstrated that it resided on the X chromosome. This was the first localization of a specific gene to a particular chromosome. Thus began Drosophila experimental genetics. The story of the initial work on white is well known but what is less well appreciated is the multiplicity of ways in which this gene has been used to explore fundamental questions in genetics. Here, I review some of the highlights of a century's productive use of white in Drosophila genetics.
Source: Genetics
Author: M M Green
Institution: University of California, Davis
Language: English
Subfield: History and Philosophy of Science
Field: Arts and Humanities
Domain: Social Sciences
Open Access status: bronze
OpenAlex ID: W1995648543