Work

Inhibition of insulin/IGF-1 receptor signaling enhances bile acid toxicity in primary hepatocytes

Year: 2005

Type: article

Source: Biochemical Pharmacology

DOI: 10.1016/j.bcp.2005.08.020

Authors: Paul Dent, Song Iy Han, Clint Mitchell, Elaine Studer, Adly Yacoub, Jennifer Grandis, Steven Grant, Geoffrey W. Krystal, Philip B. Hylemon

Institutions: Virginia Commonwealth University, University of Pittsburgh, UPMC Hillman Cancer Center, Hunter Holmes McGuire VA Medical Center

Language: English

Topic: Liver physiology and pathology

Subfield: Hepatology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: closed

Funders: National Institutes of Health, National Cancer Institute, National Institute of Diabetes and Digestive and Kidney Diseases

Awards: G240198448, G2447325627, G2809070691, LIVER/INTESTINAL METABOLISM OF BILE ACIDS/CHOLESTEROL, Carcinoma cell radiosensitization by MAPK inhibition, Signaling Pathways Regulating Epithelial Cell Survival, Genetic Modulation of Cellular Radiation Responses, Promotion of Nucleoside Analog Induced Apoptosis by HDIs, G6390103841, G63926105, G675329814, G680599012, Regulation of Hepatic SphK2 by Bile Acids: Effects on Lipid Metabolism

OpenAlex ID: W1995979697

FWCI: 1.183

Cites: 43

Cited by: 20

Related to: 10