Work

Multiple forms of H4 histone mRNA in human cells.

Year: 1980

Type: article

Abstract: Two species of H4 histone mRNA were isolated from the polysomes of S phase HeLa S3 cells. Electrophoresis under denaturing and nondenaturing conditions indicates that the two H4 mRNAs differ in size. Both mRNAs translate H4 histones in vitro, lack poly(A) at their 3' termini, and are capped at their 5' termini. Polyacrylamide gel electrophoresis and tryptic peptide analysis suggest that the polypeptides synthesized by the two mRNAs are indistinguishable.

Source: Proceedings of the National Academy of Sciences

DOI: 10.1073/pnas.77.4.1942

Authors: A C Lichtler, S Detke, I R Phillips, G S Stein, J L Stein

Language: English

Topic: Genomics and Chromatin Dynamics

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: green

OpenAlex ID: W1996011102

FWCI: 1.832

Cites: 32

Cited by: 21

Related to: 10