Work

A noninflammatory pathway for pregnancy loss: innate immune activation?

Year: 2004

Type: article

Abstract: Although the mechanisms of immune-mediated pregnancy loss are unknown, investigations are currently focused on mediators of immune activation and tissue injury at the maternal-fetal interface. A new study, however, demonstrates that systemic inflammatory mediators can induce pregnancy failure in a different way, by inhibiting ovarian hormone production, and identifies links between the immune and reproductive endocrine systems.

Source: Journal of Clinical Investigation

DOI: 10.1172/jci200422258

Author: Jane E. Salmon

Institutions: Hospital for Special Surgery, Cornell University, Weill Cornell Medicine

Language: English

Topic: Reproductive System and Pregnancy

Subfield: Immunology

Field: Immunology and Microbiology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: bronze