Work

Hexadecameric Self-Assembled Dendrimers Built from 2′-Deoxyguanosine Derivatives

Year: 2008

Type: article

Abstract: Herein we describe the construction of hexadecameric self-assembled dendrimers (SADs) using a series of dendronized 8-(m-acetylphenyl)-2'-deoxyguanosine (mAG) subunits. The azido-substituted mAG subunits were covalently linked to alkynyl polyester dendrons using a copper-catalyzed 1,3-dipolar cycloaddition reaction. Discrete SADs are formed with high fidelity and thermal stability even with the increased steric hindrance offered by the dendrons.

Source: Organic Letters

DOI: 10.1021/ol800701j

Authors: José E. Betancourt, José M. Rivera

Institutions: University of Puerto Rico at Río Piedras, University of Puerto Rico System

Language: English

Topic: Dendrimers and Hyperbranched Polymers

Subfield: Polymers and Plastics

Field: Materials Science

Domain: Physical Sciences

Open Access status: hybrid

Estimated APC paid: $4,500

Funders: National Institutes of Health, National Center for Research Resources