Work

Effects of Body Mass Index (BMI) in Children Undergoing Allogeneic Bone Marrow Transplant (BMT) for Hematologic Malignancies

Year: 2012

Type: article

Abstract: The rising incidence of pediatric obesity may significantly impact BMT outcomes for malignant diseases, as has been demonstrated in increased mortality in children undergoing BMT for aplastic anemia. Obesity may influence chemotherapy dosing and transplant related mortality (TRM). We analyzed 3,687 children ages 2-18, who received BMT for treatment of hematologic malignancies using either busulfan/cyclophosphamide (BuCy, N = 1,196) or Cy/total body irradiation-based (CyTBI, N = 2,495) conditioning, between 1990 and 2007.

Source: Transplantation and Cellular Therapy

DOI: 10.1016/j.bbmt.2011.12.081