Work

Inhibition of cisplatin‐induced vomiting by selective 5‐hydroxytryptamine M‐receptor antagonism

Year: 1986

Type: article

Abstract: MDL 72222, the selective 5-hydroxytryptamine (5-HT) M-receptor antagonist, prevented or reduced cisplatin-induced emesis in ferrets. It is suggested that cisplatin-induced, and possibly other cytotoxic drug-induced vomiting may involve a 5-HT M-receptor mechanism.

Source: British Journal of Pharmacology

DOI: 10.1111/j.1476-5381.1986.tb10228.x

Authors: Wesley D. Miner, Gareth J. Sanger

Language: English

Topic: Nausea and vomiting management

Subfield: Surgery

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W1996898160

FWCI: 41.22

Cites: 11

Cited by: 338

Related to: 10