Work

Compromised CDK1 activity sensitizes BRCA-proficient cancers to PARP inhibition

Year: 2011

Type: article

Source: Nature Medicine

DOI: 10.1038/nm.2377

Authors: Neil Johnson, Yu-Chen Li, Zandra E Walton, Katherine A Cheng, Danan Li, Scott J Rodig, Lisa A Moreau, Christine Unitt, Roderick T Bronson, Huw D Thomas, David R Newell, Alan D D'Andrea, Nicola J Curtin, Kwok-Kin Wong, Geoffrey I Shapiro

Institutions: Brigham and Women's Hospital, Harvard University, Dana-Farber Cancer Institute, Boston Children's Hospital, Newcastle University, Dana-Farber/Harvard Cancer Center

Language: English

Topic: PARP inhibition in cancer therapy

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funders: National Institute on Aging, National Cancer Institute

Awards: G1282312431, G1437721334, G3100591761, G4001869557, G4258809411, G458608165, G5415167530, G5788965486, G7630262769, G7816045031, Cyclin-Dependent Kinase Inhibition During S Phase

OpenAlex ID: W1996931025

FWCI: 10.61

Cites: 36

Cited by: 290

Related to: 10