Work

CT7/MAGE-C1 Expression and Immune Responses Following Allogeneic Transplant for Multiple Myeloma

Year: 2013

Type: article

Abstract: Cancer-testis antigen 7 (CT7, or melanoma-associated antigen (MAGE)-C1) is the most frequently and consistently expressed MAGE antigen in multiple myeloma (MM). CT7 is an independent negative prognostic factor for MM, exhibits a tissue-restricted expression pattern, and is highly expressed during all stages of disease. Consequently, CT7 is regarded as a potential target for immunotherapeutic strategies in MM.

Source: Transplantation and Cellular Therapy

DOI: 10.1016/j.bbmt.2012.11.116

Authors: Eleanor M. Tyler, Achim A. Jungbluth, Sacha Gnjatic, Richard O'Reilly, Guenther Koehne

Institutions: Cornell University, Weill Cornell Medicine, Ludwig Cancer Research, Memorial Sloan Kettering Cancer Center

Language: English

Topic: Multiple Myeloma Research and Treatments

Subfield: Hematology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $3,650