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In vivo synergy of radiation and hu14.18-IL2 immunocytokine results in a memory T cell response in a syngeneic murine melanoma model

Year: 2014
Type: article
Abstract: Meeting abstracts Tumor-specific monoclonal antibodies (mAb) are a common type of immunotherapy capable of engaging innate immune cells to elicit antibody-dependent cell-mediated cytotoxicity (ADCC). We recently demonstrated in vivo synergy between radiation (RT) and ADCC using the anti-GD2 hu14.18
DOI: 10.1186/2051-1426-2-s3-p160
Authors: Zachary S Morris, Emily Guy, David Francis, Monica Gressett, Richard Yang, Alexander Rakhmilevich, Jaquelyn Hank, Stephen Gillies, Paul Harari, Paul Sondel
Language: English
Subfield: Immunology
Open Access status: gold
Estimated APC paid: $2,490
OpenAlex ID: W1997135069
FWCI:
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Related to: 10